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Dyrk1A Is Dynamically Expressed on Subsets of Motor Neurons and in the Neuromuscular Junction: Possible Role in Down Syndrome

Individuals with Down syndrome (DS) present important motor deficits that derive from altered motor development of infants and young children. DYRK1A, a candidate gene for DS abnormalities has been implicated in motor function due to its expression in motor nuclei in the adult brain, and its overexp...

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Detalles Bibliográficos
Autores principales: Arque, Gloria, Casanovas, Anna, Dierssen, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546979/
https://www.ncbi.nlm.nih.gov/pubmed/23342120
http://dx.doi.org/10.1371/journal.pone.0054285