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Hypoxia Promotes Dopaminergic Differentiation of Mesenchymal Stem Cells and Shows Benefits for Transplantation in a Rat Model of Parkinson’s Disease

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into dopaminergic (DAergic) neurons, which is one of the major cell types damaged in Parkinson’s disease (PD). For this reason, MSCs are considered a potential cell source for PD therapy. It has been proved that hypoxia i...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Yang, Jian, Li, Haisheng, Wang, Xuan, Zhu, Lingling, Fan, Ming, Wang, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546985/
https://www.ncbi.nlm.nih.gov/pubmed/23342124
http://dx.doi.org/10.1371/journal.pone.0054296