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Signaling through the TGF Beta-Activin Receptors ALK4/5/7 Regulates Testis Formation and Male Germ Cell Development

The developing testis provides an environment that nurtures germ cell development, ultimately ensuring spermatogenesis and fertility. Impacts on this environment are considered to underlie aberrant germ cell development and formation of germ cell tumour precursors. The signaling events involved in t...

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Detalles Bibliográficos
Autores principales: Miles, Denise C., Wakeling, Stephanie I., Stringer, Jessica M., van den Bergen, Jocelyn A., Wilhelm, Dagmar, Sinclair, Andrew H., Western, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546992/
https://www.ncbi.nlm.nih.gov/pubmed/23342175
http://dx.doi.org/10.1371/journal.pone.0054606