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Bicarbonate-Dependent Secretion and Proteolytic Processing of Recombinant Myocilin

Myocilin is an extracellular glycoprotein of poorly understood function. Mutations of this protein are involved in glaucoma, an optic neuropathy characterized by a progressive and irreversible visual loss and frequently associated with elevated intraocular pressure. We previously showed that recombi...

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Detalles Bibliográficos
Autores principales: Aroca-Aguilar, José-Daniel, Martínez-Redondo, Francisco, Martín-Gil, Alba, Pintor, Jesús, Coca-Prados, Miguel, Escribano, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547000/
https://www.ncbi.nlm.nih.gov/pubmed/23342144
http://dx.doi.org/10.1371/journal.pone.0054385