miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer

miRNAs are important regulators of gene expression that are frequently deregulated in cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this process. We previously identified miRNA promoter regions active in normal mammary cell types and here we analyzed which of these...

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Detalles Bibliográficos
Autores principales: Vrba, Lukas, Muñoz-Rodríguez, José L., Stampfer, Martha R., Futscher, Bernard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547033/
https://www.ncbi.nlm.nih.gov/pubmed/23342147
http://dx.doi.org/10.1371/journal.pone.0054398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547033/
https://www.ncbi.nlm.nih.gov/pubmed/23342147
http://dx.doi.org/10.1371/journal.pone.0054398

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