Cargando…
miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer
miRNAs are important regulators of gene expression that are frequently deregulated in cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this process. We previously identified miRNA promoter regions active in normal mammary cell types and here we analyzed which of these...
Autores principales: | Vrba, Lukas, Muñoz-Rodríguez, José L., Stampfer, Martha R., Futscher, Bernard W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547033/ https://www.ncbi.nlm.nih.gov/pubmed/23342147 http://dx.doi.org/10.1371/journal.pone.0054398 |
Ejemplares similares
-
Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells
por: Vrba, Lukas, et al.
Publicado: (2010) -
Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation
por: Severson, Paul L., et al.
Publicado: (2012) -
Cell-Type Specific DNA Methylation Patterns Define Human Breast Cellular Identity
por: Novak, Petr, et al.
Publicado: (2012) -
DNA methylation changes in biomarker loci occur early in cancer progression
por: Vrba, Lukas, et al.
Publicado: (2020) -
A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers
por: Vrba, Lukas, et al.
Publicado: (2015)