Expansion on Stromal Cells Preserves the Undifferentiated State of Human Hematopoietic Stem Cells Despite Compromised Reconstitution Ability

Lack of HLA-matched hematopoietic stem cells (HSC) limits the number of patients with life-threatening blood disorders that can be treated by HSC transplantation. So far, insufficient understanding of the regulatory mechanisms governing human HSC has precluded the development of effective protocols...

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Detalles Bibliográficos
Autores principales: Magnusson, Mattias, Sierra, Maria I., Sasidharan, Rajkumar, Prashad, Sacha L., Romero, Melissa, Saarikoski, Pamela, Van Handel, Ben, Huang, Andy, Li, Xinmin, Mikkola, Hanna K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547050/
https://www.ncbi.nlm.nih.gov/pubmed/23342037
http://dx.doi.org/10.1371/journal.pone.0053912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547050/
https://www.ncbi.nlm.nih.gov/pubmed/23342037
http://dx.doi.org/10.1371/journal.pone.0053912

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