Expansion on Stromal Cells Preserves the Undifferentiated State of Human Hematopoietic Stem Cells Despite Compromised Reconstitution Ability

Lack of HLA-matched hematopoietic stem cells (HSC) limits the number of patients with life-threatening blood disorders that can be treated by HSC transplantation. So far, insufficient understanding of the regulatory mechanisms governing human HSC has precluded the development of effective protocols...

Descripción completa

Detalles Bibliográficos
Autores principales: Magnusson, Mattias, Sierra, Maria I., Sasidharan, Rajkumar, Prashad, Sacha L., Romero, Melissa, Saarikoski, Pamela, Van Handel, Ben, Huang, Andy, Li, Xinmin, Mikkola, Hanna K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547050/
https://www.ncbi.nlm.nih.gov/pubmed/23342037
http://dx.doi.org/10.1371/journal.pone.0053912

Ejemplares similares

Ejemplares similares