NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma

Cutaneous malignant melanoma is the most lethal form of skin cancer, with 5-year survival rates of <5 % for patients presenting with metastatic disease. Mechanisms underlying metastatic spread of UVR-induced melanoma are not well understood, in part due to a paucity of animal models that accurate...

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Detalles Bibliográficos
Autores principales: Jarrett, Stuart G., Novak, Marian, Harris, Nathan, Merlino, Glenn, Slominski, Andrezj, Kaetzel, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547246/
https://www.ncbi.nlm.nih.gov/pubmed/22699362
http://dx.doi.org/10.1007/s10585-012-9495-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547246/
https://www.ncbi.nlm.nih.gov/pubmed/22699362
http://dx.doi.org/10.1007/s10585-012-9495-z

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