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NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma
Cutaneous malignant melanoma is the most lethal form of skin cancer, with 5-year survival rates of <5 % for patients presenting with metastatic disease. Mechanisms underlying metastatic spread of UVR-induced melanoma are not well understood, in part due to a paucity of animal models that accurate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547246/ https://www.ncbi.nlm.nih.gov/pubmed/22699362 http://dx.doi.org/10.1007/s10585-012-9495-z |