A Model for Migratory B Cell Oscillations from Receptor Down-Regulation Induced by External Chemokine Fields

A long-standing paradigm in B cell immunology is that effective somatic hypermutation and affinity maturation require cycling between the dark zone and light zone of the germinal center. The cyclic re-entry hypothesis was first proposed based on considerations of the efficiency of affinity maturatio...

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Detalles Bibliográficos
Autores principales: Chan, Cliburn, Billard, Matthew, Ramirez, Samuel A., Schmidl, Harald, Monson, Eric, Kepler, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547247/
https://www.ncbi.nlm.nih.gov/pubmed/23296998
http://dx.doi.org/10.1007/s11538-012-9799-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547247/
https://www.ncbi.nlm.nih.gov/pubmed/23296998
http://dx.doi.org/10.1007/s11538-012-9799-9

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