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Examination of soluble integrin resistant mutants of foot-and-mouth disease virus

BACKGROUND: Foot-and-mouth disease virus (FMDV) initiates infection via recognition of one of at least four cell-surface integrin molecules α(v)β(1), α(v)β(3), α(v)β(6), or α(v)β(8) by a highly conserved Arg-Gly-Asp (RGD) amino acid sequence motif located in the G-H loop of VP1. Within the animal ho...

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Detalles Bibliográficos
Autores principales: Lawrence, Paul, LaRocco, Michael, Baxt, Barry, Rieder, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547720/
https://www.ncbi.nlm.nih.gov/pubmed/23282061
http://dx.doi.org/10.1186/1743-422X-10-2