Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis

BACKGROUND: Stress of the endoplasmic reticulum (ER) leading to activation of the unfolded protein response (UPR) and alveolar epithelial cell (AEC) apoptosis may play a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Our objectives were to determine whether circulating caspase-clea...

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Detalles Bibliográficos
Autores principales: Cha, Seung-Ick, Ryerson, Christopher J, Lee, Joyce S, Kukreja, Jasleen, Barry, Sophia S, Jones, Kirk D, Elicker, Brett M, Kim, Dong Soon, Papa, Feroz R, Collard, Harold R, Wolters, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547729/
https://www.ncbi.nlm.nih.gov/pubmed/23167970
http://dx.doi.org/10.1186/1465-9921-13-105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547729/
https://www.ncbi.nlm.nih.gov/pubmed/23167970
http://dx.doi.org/10.1186/1465-9921-13-105

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