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Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?
The Nonhomologous end joining pathway is essential for efficient repair of chromosome double strand breaks. This pathway consequently plays a key role in cellular resistance to break-inducing exogenous agents, as well as in the developmentally-programmed recombinations that are required for adaptive...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547747/ https://www.ncbi.nlm.nih.gov/pubmed/23276302 http://dx.doi.org/10.1186/2041-9414-3-10 |