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Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

The Nonhomologous end joining pathway is essential for efficient repair of chromosome double strand breaks. This pathway consequently plays a key role in cellular resistance to break-inducing exogenous agents, as well as in the developmentally-programmed recombinations that are required for adaptive...

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Detalles Bibliográficos
Autores principales: Strande, Natasha Tiffany, Waters, Crystal Ann, Ramsden, Dale A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547747/
https://www.ncbi.nlm.nih.gov/pubmed/23276302
http://dx.doi.org/10.1186/2041-9414-3-10