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Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling

BACKGROUND: Both chronic hypoxia and allergic inflammation induce vascular remodeling in the lung, but only chronic hypoxia appears to cause PH. We investigate the nature of the vascular remodeling and the expression and role of hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in explaining this...

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Detalles Bibliográficos
Autores principales: Angelini, Daniel J, Su, Qingning, Yamaji-Kegan, Kazuyo, Fan, Chunling, Skinner, John T, Poloczek, Andre, El-Haddad, Hazim, Cheadle, Chris, Johns, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547770/
https://www.ncbi.nlm.nih.gov/pubmed/23289668
http://dx.doi.org/10.1186/1465-9921-14-1