Cargando…

A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study

Genetic variants in intron 1 of the fat mass– and obesity-associated (FTO) gene have been consistently associated with body mass index (BMI) in Europeans. However, follow-up studies in African Americans (AA) have shown no support for some of the most consistently BMI–associated FTO index single nucl...

Descripción completa

Detalles Bibliográficos
Autores principales: Peters, Ulrike, North, Kari E., Sethupathy, Praveen, Buyske, Steve, Haessler, Jeff, Jiao, Shuo, Fesinmeyer, Megan D., Jackson, Rebecca D., Kuller, Lew H., Rajkovic, Aleksandar, Lim, Unhee, Cheng, Iona, Schumacher, Fred, Wilkens, Lynne, Li, Rongling, Monda, Keri, Ehret, Georg, Nguyen, Khanh-Dung H., Cooper, Richard, Lewis, Cora E., Leppert, Mark, Irvin, Marguerite R., Gu, C. Charles, Houston, Denise, Buzkova, Petra, Ritchie, Marylyn, Matise, Tara C., Le Marchand, Loic, Hindorff, Lucia A., Crawford, Dana C., Haiman, Christopher A., Kooperberg, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547789/
https://www.ncbi.nlm.nih.gov/pubmed/23341774
http://dx.doi.org/10.1371/journal.pgen.1003171