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Evolutionary Optimization of Protein Folding

Nature has shaped the make up of proteins since their appearance, [Image: see text]3.8 billion years ago. However, the fundamental drivers of structural change responsible for the extraordinary diversity of proteins have yet to be elucidated. Here we explore if protein evolution affects folding spee...

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Detalles Bibliográficos
Autores principales: Debès, Cédric, Wang, Minglei, Caetano-Anollés, Gustavo, Gräter, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547816/
https://www.ncbi.nlm.nih.gov/pubmed/23341762
http://dx.doi.org/10.1371/journal.pcbi.1002861