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Tbx2 Controls Lung Growth by Direct Repression of the Cell Cycle Inhibitor Genes Cdkn1a and Cdkn1b

Vertebrate organ development relies on the precise spatiotemporal orchestration of proliferation rates and differentiation patterns in adjacent tissue compartments. The underlying integration of patterning and cell cycle control during organogenesis is insufficiently understood. Here, we have invest...

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Detalles Bibliográficos
Autores principales: Lüdtke, Timo H-W., Farin, Henner F., Rudat, Carsten, Schuster-Gossler, Karin, Petry, Marianne, Barnett, Phil, Christoffels, Vincent M., Kispert, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547831/
https://www.ncbi.nlm.nih.gov/pubmed/23341776
http://dx.doi.org/10.1371/journal.pgen.1003189