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Telomerase Is Required for Zebrafish Lifespan

Telomerase activity is restricted in humans. Consequentially, telomeres shorten in most cells throughout our lives. Telomere dysfunction in vertebrates has been primarily studied in inbred mice strains with very long telomeres that fail to deplete telomeric repeats during their lifetime. It is, ther...

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Detalles Bibliográficos
Autores principales: Henriques, Catarina M., Carneiro, Madalena C., Tenente, Inês M., Jacinto, António, Ferreira, Miguel Godinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547866/
https://www.ncbi.nlm.nih.gov/pubmed/23349637
http://dx.doi.org/10.1371/journal.pgen.1003214