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Directed Pancreatic Acinar Differentiation of Mouse Embryonic Stem Cells via Embryonic Signalling Molecules and Exocrine Transcription Factors

Pluripotent embryonic stem cells (ESC) are a promising cellular system for generating an unlimited source of tissue for the treatment of chronic diseases and valuable in vitro differentiation models for drug testing. Our aim was to direct differentiation of mouse ESC into pancreatic acinar cells, wh...

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Detalles Bibliográficos
Autores principales: Delaspre, Fabien, Massumi, Mohammad, Salido, Marta, Soria, Bernat, Ravassard, Philippe, Savatier, Pierre, Skoudy, Anouchka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547908/
https://www.ncbi.nlm.nih.gov/pubmed/23349836
http://dx.doi.org/10.1371/journal.pone.0054243