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Alteration of JNK-1 Signaling in Skeletal Muscle Fails to Affect Glucose Homeostasis and Obesity-Associated Insulin Resistance in Mice

Obesity and associated metabolic disturbances, such as increased circulating fatty acids cause prolonged low grade activation of inflammatory signaling pathways in liver, skeletal muscle, adipose tissue and even in the CNS. Activation of inflammatory pathways in turn impairs insulin signaling, ultim...

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Detalles Bibliográficos
Autores principales: Pal, Martin, Wunderlich, Claudia M., Spohn, Gabriele, Brönneke, Hella S., Schmidt-Supprian, Marc, Wunderlich, F. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547909/
https://www.ncbi.nlm.nih.gov/pubmed/23349837
http://dx.doi.org/10.1371/journal.pone.0054247