Simultaneous Measurement of Amyloid Fibril Formation by Dynamic Light Scattering and Fluorescence Reveals Complex Aggregation Kinetics

An apparatus that combines dynamic light scattering and Thioflavin T fluorescence detection is used to simultaneously probe fibril formation in polyglutamine peptides, the aggregating subunit associated with Huntington's disease, in vitro. Huntington's disease is a neurodegenerative disord...

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Detalles Bibliográficos
Autores principales: Streets, Aaron M., Sourigues, Yannick, Kopito, Ron R., Melki, Ronald, Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547910/
https://www.ncbi.nlm.nih.gov/pubmed/23349924
http://dx.doi.org/10.1371/journal.pone.0054541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547910/
https://www.ncbi.nlm.nih.gov/pubmed/23349924
http://dx.doi.org/10.1371/journal.pone.0054541

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