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Simultaneous Measurement of Amyloid Fibril Formation by Dynamic Light Scattering and Fluorescence Reveals Complex Aggregation Kinetics

An apparatus that combines dynamic light scattering and Thioflavin T fluorescence detection is used to simultaneously probe fibril formation in polyglutamine peptides, the aggregating subunit associated with Huntington's disease, in vitro. Huntington's disease is a neurodegenerative disord...

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Detalles Bibliográficos
Autores principales:	Streets, Aaron M., Sourigues, Yannick, Kopito, Ron R., Melki, Ronald, Quake, Stephen R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547910/ https://www.ncbi.nlm.nih.gov/pubmed/23349924 http://dx.doi.org/10.1371/journal.pone.0054541

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