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The Non-Peptidic Part Determines the Internalization Mechanism and Intracellular Trafficking of Peptide Amphiphiles

BACKGROUND: Peptide amphiphiles (PAs) are a class of amphiphilic molecules able to self-assemble into nanomaterials that have shown efficient in vivo targeted delivery. Understanding the interactions of PAs with cells and the mechanisms of their internalization and intracellular trafficking is criti...

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Detalles Bibliográficos
Autores principales: Missirlis, Dimitris, Teesalu, Tambet, Black, Matthew, Tirrell, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547919/
https://www.ncbi.nlm.nih.gov/pubmed/23349939
http://dx.doi.org/10.1371/journal.pone.0054611