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The Liver X Receptor Agonist GW3965 Improves Recovery from Mild Repetitive Traumatic Brain Injury in Mice Partly through Apolipoprotein E

Traumatic brain injury (TBI) increases Alzheimer’s disease (AD) risk and leads to the deposition of neurofibrillary tangles and amyloid deposits similar to those found in AD. Agonists of Liver X receptors (LXRs), which regulate the expression of many genes involved in lipid homeostasis and inflammat...

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Detalles Bibliográficos
Autores principales: Namjoshi, Dhananjay R., Martin, Georgina, Donkin, James, Wilkinson, Anna, Stukas, Sophie, Fan, Jianjia, Carr, Michael, Tabarestani, Sepideh, Wuerth, Kelli, Hancock, Robert E. W., Wellington, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547922/
https://www.ncbi.nlm.nih.gov/pubmed/23349715
http://dx.doi.org/10.1371/journal.pone.0053529