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Transforming Growth Factor β Neutralization Ameliorates Pre-Existing Hepatic Fibrosis and Reduces Cholangiocarcinoma in Thioacetamide-Treated Rats

Considerable evidence has demonstrated that transforming growth factor β (TGF-β) plays a key role in hepatic fibrosis, the final common pathway for a variety of chronic liver diseases leading to liver insufficiency. Although a few studies have reported that blocking TGF-β with soluble receptors or s...

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Detalles Bibliográficos
Autores principales: Ling, Hong, Roux, Eric, Hempel, Donna, Tao, Jingzang, Smith, Mandy, Lonning, Scott, Zuk, Anna, Arbeeny, Cynthia, Ledbetter, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547926/
https://www.ncbi.nlm.nih.gov/pubmed/23349909
http://dx.doi.org/10.1371/journal.pone.0054499