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Differential Effects of Rapamycin and Dexamethasone in Mouse Models of Established Allergic Asthma

The mammalian target of rapamycin (mTOR) plays an important role in cell growth/differentiation, integrating environmental cues, and regulating immune responses. Our lab previously demonstrated that inhibition of mTOR with rapamycin prevented house dust mite (HDM)-induced allergic asthma in mice. He...

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Detalles Bibliográficos
Autores principales: Mushaben, Elizabeth M., Brandt, Eric B., Hershey, Gurjit K. Khurana, Le Cras, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547928/
https://www.ncbi.nlm.nih.gov/pubmed/23349887
http://dx.doi.org/10.1371/journal.pone.0054426