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Metabolic profiling in Caenorhabditis elegans provides an unbiased approach to investigations of dosage dependent lead toxicity

The nematode, Caenorhabditis elegans (CE), serves as a model system in which to explore the impact of particularly low-levels of lead [250, 500, 1000 and 2000 parts per million (ppm) (1.4 × 10(−6) M to 1.1 × 10(−5) M/nematode)] on specific metabolic pathways and processes. Chromatographic profiles o...

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Detalles Bibliográficos
Autores principales: Sudama, Gita, Zhang, John, Isbister, Jenefir, Willett, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548106/
https://www.ncbi.nlm.nih.gov/pubmed/23335868
http://dx.doi.org/10.1007/s11306-012-0438-0