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Metabolic profiling in Caenorhabditis elegans provides an unbiased approach to investigations of dosage dependent lead toxicity
The nematode, Caenorhabditis elegans (CE), serves as a model system in which to explore the impact of particularly low-levels of lead [250, 500, 1000 and 2000 parts per million (ppm) (1.4 × 10(−6) M to 1.1 × 10(−5) M/nematode)] on specific metabolic pathways and processes. Chromatographic profiles o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548106/ https://www.ncbi.nlm.nih.gov/pubmed/23335868 http://dx.doi.org/10.1007/s11306-012-0438-0 |