Nonlinear Fitness Consequences of Variation in Expression Level of a Eukaryotic Gene

Levels of gene expression show considerable variation in eukaryotes, but no fine-scale maps have been made of the fitness consequences of such variation in controlled genetic backgrounds and environments. To address this, we assayed fitness at many levels of up- and down-regulated expression of a si...

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Detalles Bibliográficos
Autores principales: Rest, Joshua S., Morales, Christopher M., Waldron, John B., Opulente, Dana A., Fisher, Julius, Moon, Seungjae, Bullaughey, Kevin, Carey, Lucas B., Dedousis, Demitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548308/
https://www.ncbi.nlm.nih.gov/pubmed/23104081
http://dx.doi.org/10.1093/molbev/mss248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548308/
https://www.ncbi.nlm.nih.gov/pubmed/23104081
http://dx.doi.org/10.1093/molbev/mss248

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