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Nonlinear Fitness Consequences of Variation in Expression Level of a Eukaryotic Gene
Levels of gene expression show considerable variation in eukaryotes, but no fine-scale maps have been made of the fitness consequences of such variation in controlled genetic backgrounds and environments. To address this, we assayed fitness at many levels of up- and down-regulated expression of a si...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548308/ https://www.ncbi.nlm.nih.gov/pubmed/23104081 http://dx.doi.org/10.1093/molbev/mss248 |