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Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin. Pyomelanin is produced during tyrosine catabolism via accumulation of homogentisic acid. Although pyomelanin protects the fungus against r...

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Detalles Bibliográficos
Autores principales: Heinekamp, Thorsten, Thywißen, Andreas, Macheleidt, Juliane, Keller, Sophia, Valiante, Vito, Brakhage, Axel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548413/
https://www.ncbi.nlm.nih.gov/pubmed/23346079
http://dx.doi.org/10.3389/fmicb.2012.00440