Enhanced expression of WD repeat-containing protein 35 (WDR35) stimulated by domoic acid in rat hippocampus: involvement of reactive oxygen species generation and p38 mitogen-activated protein kinase activation

BACKGROUND: Domoic acid (DA) is an excitatory amino acid analogue of kainic acid (KA) that acts via activation of glutamate receptors to elicit a rapid and potent excitotoxic response, resulting in neuronal cell death. Recently, DA was shown to elicit reactive oxygen species (ROS) production and ind...

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Detalles Bibliográficos
Autores principales: Tsunekawa, Koji, Kondo, Fumio, Okada, Teruhiko, Feng, Guo-Gang, Huang, Lei, Ishikawa, Naohisa, Okada, Shoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548691/
https://www.ncbi.nlm.nih.gov/pubmed/23289926
http://dx.doi.org/10.1186/1471-2202-14-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548691/
https://www.ncbi.nlm.nih.gov/pubmed/23289926
http://dx.doi.org/10.1186/1471-2202-14-4

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