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The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy

BACKGROUND: The ubiquitin ligase COP1, COnstitutively Photomorphogenic 1, functions in many biological responses in mammalian cells, but its downstream pathway remains unclear. RESULTS: Here, we identified FIP200, a key regulator of mammalian autophagy, as a novel COP1-interacting protein by yeast t...

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Detalles Bibliográficos
Autores principales: Kobayashi, Saori, Yoneda-Kato, Noriko, Itahara, Nagisa, Yoshida, Akihiro, Kato, Jun-ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548756/
https://www.ncbi.nlm.nih.gov/pubmed/23289756
http://dx.doi.org/10.1186/1471-2091-14-1