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Separate Developmental Programs for HLA-A and -B Cell Surface Expression during Differentiation from Embryonic Stem Cells to Lymphocytes, Adipocytes and Osteoblasts

A major problem of allogeneic stem cell therapy is immunologically mediated graft rejection. HLA class I A, B, and Cw antigens are crucial factors, but little is known of their respective expression on stem cells and their progenies. We have recently shown that locus-specific expression (HLA-A, but...

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Detalles Bibliográficos
Autores principales: Sabir, Hardee J., Nehlin, Jan O., Qanie, Diyako, Harkness, Linda, Prokhorova, Tatyana A., Blagoev, Blagoy, Kassem, Moustapha, Isa, Adiba, Barington, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548781/
https://www.ncbi.nlm.nih.gov/pubmed/23349864
http://dx.doi.org/10.1371/journal.pone.0054366