ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

The respiratory epithelium is subject to continuous environmental stress and its responses to injury or infection are largely mediated by transactivation of the epidermal growth factor receptor (EGFR) and downstream signaling cascades. Based on previous studies indicating involvement of ATP-dependen...

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Detalles Bibliográficos
Autores principales: Sham, Derek, Wesley, Umadevi V., Hristova, Milena, van der Vliet, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548788/
https://www.ncbi.nlm.nih.gov/pubmed/23349873
http://dx.doi.org/10.1371/journal.pone.0054391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548788/
https://www.ncbi.nlm.nih.gov/pubmed/23349873
http://dx.doi.org/10.1371/journal.pone.0054391

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