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Cyclic AMP Enhances TGFβ Responses of Breast Cancer Cells by Upregulating TGFβ Receptor I Expression

Cellular functions are regulated by complex networks of many different signaling pathways. The TGFβ and cAMP pathways are of particular importance in tumor progression. We analyzed the cross-talk between these pathways in breast cancer cells in 2D and 3D cultures. We found that cAMP potentiated TGFβ...

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Detalles Bibliográficos
Autores principales: Oerlecke, Ilka, Bauer, Elke, Dittmer, Angela, Leyh, Benjamin, Dittmer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548810/
https://www.ncbi.nlm.nih.gov/pubmed/23349840
http://dx.doi.org/10.1371/journal.pone.0054261