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Cyclic AMP Enhances TGFβ Responses of Breast Cancer Cells by Upregulating TGFβ Receptor I Expression
Cellular functions are regulated by complex networks of many different signaling pathways. The TGFβ and cAMP pathways are of particular importance in tumor progression. We analyzed the cross-talk between these pathways in breast cancer cells in 2D and 3D cultures. We found that cAMP potentiated TGFβ...
Autores principales: | Oerlecke, Ilka, Bauer, Elke, Dittmer, Angela, Leyh, Benjamin, Dittmer, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548810/ https://www.ncbi.nlm.nih.gov/pubmed/23349840 http://dx.doi.org/10.1371/journal.pone.0054261 |
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