Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...

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Detalles Bibliográficos
Autores principales: Meng, Jingjing, Yu, Haidong, Ma, Jing, Wang, Jinghua, Banerjee, Santanu, Charboneau, Rick, Barke, Roderick A., Roy, Sabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548814/
https://www.ncbi.nlm.nih.gov/pubmed/23349783
http://dx.doi.org/10.1371/journal.pone.0054040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548814/
https://www.ncbi.nlm.nih.gov/pubmed/23349783
http://dx.doi.org/10.1371/journal.pone.0054040

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