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Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner
Opiates are among the most prescribed drugs for pain management. However, morphine use or abuse results in significant gut bacterial translocation and predisposes patients to serious infections with gut origin. The mechanism underlying this defect is still unknown. In this report, we investigated th...
Autores principales: | Meng, Jingjing, Yu, Haidong, Ma, Jing, Wang, Jinghua, Banerjee, Santanu, Charboneau, Rick, Barke, Roderick A., Roy, Sabita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548814/ https://www.ncbi.nlm.nih.gov/pubmed/23349783 http://dx.doi.org/10.1371/journal.pone.0054040 |
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