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Mast Cells Express 11β-hydroxysteroid Dehydrogenase Type 1: A Role in Restraining Mast Cell Degranulation

Mast cells are key initiators of allergic, anaphylactic and inflammatory reactions, producing mediators that affect vascular permeability, angiogenesis and fibrosis. Glucocorticoid pharmacotherapy reduces mast cell number, maturation and activation but effects at physiological levels are unknown. Wi...

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Detalles Bibliográficos
Autores principales: Coutinho, Agnes E., Brown, Jeremy K., Yang, Fu, Brownstein, David G., Gray, Mohini, Seckl, Jonathan R., Savill, John S., Chapman, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548897/
https://www.ncbi.nlm.nih.gov/pubmed/23349944
http://dx.doi.org/10.1371/journal.pone.0054640