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Mast Cells Express 11β-hydroxysteroid Dehydrogenase Type 1: A Role in Restraining Mast Cell Degranulation
Mast cells are key initiators of allergic, anaphylactic and inflammatory reactions, producing mediators that affect vascular permeability, angiogenesis and fibrosis. Glucocorticoid pharmacotherapy reduces mast cell number, maturation and activation but effects at physiological levels are unknown. Wi...
Autores principales: | Coutinho, Agnes E., Brown, Jeremy K., Yang, Fu, Brownstein, David G., Gray, Mohini, Seckl, Jonathan R., Savill, John S., Chapman, Karen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548897/ https://www.ncbi.nlm.nih.gov/pubmed/23349944 http://dx.doi.org/10.1371/journal.pone.0054640 |
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