Cargando…
Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment
BACKGROUND: Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. Ho...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549285/ https://www.ncbi.nlm.nih.gov/pubmed/23272650 http://dx.doi.org/10.1186/1471-2180-12-307 |