Cargando…

Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

BACKGROUND: Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Dake, Dong, Peiling, Zhang, Ke, Deng, Libin, Bach, Christian, Chen, Wei, Li, Feifei, Protzer, Ulrike, Ding, Huiguo, Zeng, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549285/ https://www.ncbi.nlm.nih.gov/pubmed/23272650 http://dx.doi.org/10.1186/1471-2180-12-307

Ejemplares similares

HBV preS deletion mapping using deep sequencing demonstrates a unique association with viral markers
por: Suzuki, Yuichiro, et al.
Publicado: (2019)

Enigmatic PreS deletions in hepatitis B virus DNA
por: Gerlich, Wolfram H., et al.
Publicado: (2020)

HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion Site
por: Zhang, Dake, et al.
Publicado: (2021)

Prevalent HBV point mutations and mutation combinations at BCP/preC region and their association with liver disease progression
por: Zhang, Dake, et al.
Publicado: (2010)

The emerging role of hepatitis B virus Pre-S2 deletion mutant proteins in HBV tumorigenesis
por: Su, Ih-Jen, et al.
Publicado: (2014)

Hypomethylation in HBV integration regions aids non-invasive surveillance to hepatocellular carcinoma by low-pass genome-wide bisulfite sequencing
por: Zhang, Haikun, et al.
Publicado: (2020)

Pre-S Deletions are Predominant Quasispecies in HIV/HBV Infection: Quasispecies Perspective
por: Nie, Yuan, et al.
Publicado: (2020)

Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients
por: Thi Cam Huong, Nguyen, et al.
Publicado: (2022)

Sparse logistic regression revealed the associations between HBV PreS quasispecies and hepatocellular carcinoma
por: Jia, Jian-an, et al.
Publicado: (2022)

128 Cure of HBV infection: can APOBEC3 deaminases mediate it?
por: Protzer, Ulrike
Publicado: (2014)

Whole-Genome Sequences of Variants of Bacillus anthracis Sterne and Their Toxin Gene Deletion Mutants
por: Staab, A., et al.
Publicado: (2017)

Practical Method for Isolation of Phage Deletion Mutants
por: Gutiérrez, Diana, et al.
Publicado: (2018)

Lost Small Envelope Protein Expression from Naturally Occurring PreS1 Deletion Mutants of Hepatitis B Virus Is Often Accompanied by Increased HBx and Core Protein Expression as Well as Genome Replication
por: Fu, Shuwen, et al.
Publicado: (2021)

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection
por: Kosinska, Anna D., et al.
Publicado: (2021)

HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling
por: Liu, Wenbin, et al.
Publicado: (2022)

Association of preS/S Mutations with Occult Hepatitis B Virus (HBV) Infection in South Korea: Transmission Potential of Distinct Occult HBV Variants
por: Kim, Hong, et al.
Publicado: (2015)

The Strategy of Conditionally Replicating Adenovirus-Mediated PreS2 Mini-Antibody Expression Has Dual Effects of Inhibiting HBV Infection and Preventing Hepatocellular Carcinoma
por: Ye, Ziheng, et al.
Publicado: (2021)

Modular epistasis and the compensatory evolution of gene deletion mutants
por: Rojas Echenique, José I., et al.
Publicado: (2019)

Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins
por: Debelec-Butuner, Bilge, et al.
Publicado: (2022)

IFN-α-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection
por: Li, Yong, et al.
Publicado: (2017)

Diverse Effects of the NTCP p.Ser267Phe Variant on Disease Progression During Chronic HBV Infection and on HBV preS1 Variability
por: Yang, Fangji, et al.
Publicado: (2019)

A Soybean Deletion Mutant That Moderates the Repression of Flowering by Cool Temperatures
por: Zhang, Jingyu, et al.
Publicado: (2020)

In Vivo Expression of the PTB-deleted Odin Mutant Results in Hydrocephalus
por: Park, Sunjung, et al.
Publicado: (2015)

Cariogenicity of Streptococcus mutans Glucan-Binding Protein Deletion Mutants
por: Lynch, David J, et al.
Publicado: (2013)

Safety and Efficacy of Felid Herpesvirus-1 Deletion Mutants in Cats
por: Lee, Yao, et al.
Publicado: (2021)

Whole-Gene Deletions of FZD4 Cause Familial Exudative Vitreoretinopathy
por: Huang, Li, et al.
Publicado: (2021)

FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation
por: Yan, Xiaoqing, et al.
Publicado: (2015)

Whole-genome analysis of Fusarium graminearum insertional mutants identifies virulence associated genes and unmasks untagged chromosomal deletions
por: Urban, Martin, et al.
Publicado: (2015)

HBV preS2 promotes the expression of TAZ via miRNA-338-3p to enhance the tumorigenesis of hepatocellular carcinoma
por: Liu, Peng, et al.
Publicado: (2015)

An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants
por: Choi, Kyoung-Hee, et al.
Publicado: (2005)

Update on the Keio collection of Escherichia coli single-gene deletion mutants
por: Yamamoto, Natsuko, et al.
Publicado: (2009)

Deletion Mutants of VPg Reveal New Cytopathology Determinants in a Picornavirus
por: Arias, Armando, et al.
Publicado: (2010)

A prototrophic deletion mutant collection for yeast metabolomics and systems biology
por: Mülleder, Michael, et al.
Publicado: (2012)

FNBtools: A Software to Identify Homozygous Lesions in Deletion Mutant Populations
por: Sun, Liang, et al.
Publicado: (2018)

Efficient isolation of mouse deletion mutant embryonic stem cells by CRISPR
por: Liu, Yuhan, et al.
Publicado: (2022)

An Exome-seq Based Tool for Mapping and Selection of Candidate Genes in Maize Deletion Mutants
por: Jia, Shangang, et al.
Publicado: (2018)

Clinical detection of deletion structural variants in whole-genome sequences
por: Noll, Aaron C, et al.
Publicado: (2016)

PReS-FINAL-2010: Predictive value of whole-body MRI in juvenile dermatomyositis
por: Malattia, C, et al.
Publicado: (2013)

Hepatitis B Virus Pre-S Gene Deletions and Pre-S Deleted Proteins: Clinical and Molecular Implications in Hepatocellular Carcinoma
por: Lin, Yueh-Te, et al.
Publicado: (2021)

Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA
por: Sugawara, Hiroko, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2e309htc47e21gi8dgtoonkcb3