Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb

BACKGROUND: The receptor for the cytokine TWEAK (TweakR) is a cell surface member of the tumor necrosis factor receptor superfamily with diverse biological roles. TNFRSF family members are appealing therapeutic targets in oncology due to their aberrant expression and function in tumor cells. The goa...

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Detalles Bibliográficos
Autores principales: Chao, Debra T., Su, Mian, Tanlimco, Sonia, Sho, Mien, Choi, Donghee, Fox, Mel, Ye, Shiming, Hsi, Eric D., Durkin, Lisa, Yin, Johnny, Zhang, Yongke, Kim, Han, Starling, Gary C., Culp, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549414/
https://www.ncbi.nlm.nih.gov/pubmed/23073510
http://dx.doi.org/10.1007/s00432-012-1332-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549414/
https://www.ncbi.nlm.nih.gov/pubmed/23073510
http://dx.doi.org/10.1007/s00432-012-1332-x

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