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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression()

We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains of patients with Alzheimer's disease (AD)....

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Detalles Bibliográficos
Autores principales: Silver, Matt, Janousova, Eva, Hua, Xue, Thompson, Paul M., Montana, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549495/
https://www.ncbi.nlm.nih.gov/pubmed/22982105
http://dx.doi.org/10.1016/j.neuroimage.2012.08.002