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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression()
We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains of patients with Alzheimer's disease (AD)....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549495/ https://www.ncbi.nlm.nih.gov/pubmed/22982105 http://dx.doi.org/10.1016/j.neuroimage.2012.08.002 |