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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression()
We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains of patients with Alzheimer's disease (AD)....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549495/ https://www.ncbi.nlm.nih.gov/pubmed/22982105 http://dx.doi.org/10.1016/j.neuroimage.2012.08.002 |