Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect

Cystic fibrosis (CF) patients harboring the most common deletion mutation of the CF transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset of CF patients who genetically carry plasma membrane (PM)-re...

Descripción completa

Detalles Bibliográficos
Autores principales: Villella, Valeria Rachela, Esposito, Speranza, Bruscia, Emanuela M., Maiuri, Maria Chiara, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549520/
https://www.ncbi.nlm.nih.gov/pubmed/23346057
http://dx.doi.org/10.3389/fphar.2013.00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549520/
https://www.ncbi.nlm.nih.gov/pubmed/23346057
http://dx.doi.org/10.3389/fphar.2013.00001

Ejemplares similares