Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast

Activation of mitosis promoting factor (MPF) drives mitotic commitment(1). In human cells active MPF appears first on centrosomes(2). We show that local activation of MPF on the equivalent organelle of fission yeast, the spindle pole body (SPB), promotes Polo kinase activity at the SPBs long before...

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Detalles Bibliográficos
Autores principales: Grallert, Agnes, Patel, Avinash, Tallada, Victor A., Chan, Kuan Yoow, Bagley, Steven, Krapp, Andrea, Simanis, Viesturs, Hagan, Iain M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549529/
https://www.ncbi.nlm.nih.gov/pubmed/23222840
http://dx.doi.org/10.1038/ncb2633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549529/
https://www.ncbi.nlm.nih.gov/pubmed/23222840
http://dx.doi.org/10.1038/ncb2633

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