The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

Regulated intramembrane proteolysis is a central cellular process involved in signal transduction and membrane protein turnover. The presenilin homologue signal-peptide-peptidase-like 2a (SPPL2a) has been implicated in the cleavage of type 2 transmembrane proteins. We show that the invariant chain (...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneppenheim, Janna, Dressel, Ralf, Hüttl, Susann, Lüllmann-Rauch, Renate, Engelke, Michael, Dittmann, Kai, Wienands, Jürgen, Eskelinen, Eeva-Liisa, Hermans-Borgmeyer, Irm, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549707/
https://www.ncbi.nlm.nih.gov/pubmed/23267015
http://dx.doi.org/10.1084/jem.20121069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549707/
https://www.ncbi.nlm.nih.gov/pubmed/23267015
http://dx.doi.org/10.1084/jem.20121069

Ejemplares similares