Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching

DNA double-strand breaks (DSBs) are byproducts of normal cellular metabolism and obligate intermediates in antigen receptor diversification reactions. These lesions are potentially dangerous because they can lead to deletion of genetic material or chromosome translocation. The chromatin-binding prot...

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Detalles Bibliográficos
Autores principales: Bothmer, Anne, Rommel, Philipp C., Gazumyan, Anna, Polato, Federica, Reczek, Colleen R., Muellenbeck, Matthias F., Schaetzlein, Sonja, Edelmann, Winfried, Chen, Phang-Lang, Brosh, Robert M., Casellas, Rafael, Ludwig, Thomas, Baer, Richard, Nussenzweig, André, Nussenzweig, Michel C., Robbiani, Davide F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549709/
https://www.ncbi.nlm.nih.gov/pubmed/23254285
http://dx.doi.org/10.1084/jem.20121975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549709/
https://www.ncbi.nlm.nih.gov/pubmed/23254285
http://dx.doi.org/10.1084/jem.20121975

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